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Press releases

 

VRT
Bedrijf uit Mechelen onderzoekt of lichaamstemperatuur van 41,5 graden kankercellen kan helpen te vernietigen
https://www.vrt.be/vrtnws/nl/2022/01/26/mechels-bedrijf-voert-onderzoek-naar-kankerbehandeling-met-hitte/

HLN
Kankeronderzoeker test hittetherapie nadat hij zijn moeder verloor aan pancreaskanker: “Zij zou dit prachtig gevonden hebben”
https://www.hln.be/binnenland/kankeronderzoeker-test-hittetherapie-nadat-hij-zijn-moeder-verloor-aan-pancreaskanker-zij-zou-dit-prachtig-gevonden-hebben~afce5f18/

HBVL
Bijna 12 miljoen geïnvesteerd in Belgische hittetechnologie voor kankerbestrijding.
https://www.hbvl.be/cnt/dmf20220125_92989586

DeMorgen
Met hittetherapie hopen we de levensverwachting én levenskwaliteit van kankerpatiënten te verbeteren
https://www.demorgen.be/nieuws/met-hittetherapie-hopen-we-de-levensverwachting-en-levenskwaliteit-van-kankerpatienten-te-verbeteren~bfce5f18/

De tijd
Leuvens medtechbedrijf test hittetherapie om uitgezaaide kanker te bestrijden
https://www.tijd.be/ondernemen/farma-biotech/leuvens-medtechbedrijf-test-hittetherapie-om-uitgezaaide-kanker-te-bestrijden/10361741.html

The Brussels Times
Leuven tech company raises €4 million for clinical tests of cancer therapy
https://www.brusselstimes.com/belgium-all-news/203209/leuven-tech-company-raises-e4-million-for-clinical-tests-of-cancer-therapy

KanaalZ
Leuvense medtechbedrijf ElmediX ontwikkelt hittebehandeling voor kankerpatiënten.
https://kanaalz.knack.be/nieuws/leuvense-medtechbedrijf-elmedix-ontwikkelt-hittebehandeling-voor-kankerpatienten/video-normal-1826765.html

Bloovi
Spin-off UA haalt 12 miljoen euro op voor innovatieve kankertechnologie
https://www.bloovi.be/artikels/ondernemersnieuws/2022/spin-off-ua-haalt-12-miljoen-euro-op-voor-innovatieve-kankertechnologie

BNDeStem
Halsterse prof wil uitgezaaide kanker, de ziekte waaraan zijn moeder overleed, te lijf gaan met hitte
https://www.bndestem.nl/bergen-op-zoom/halsterse-prof-wil-uitgezaaide-kanker-de-ziekte-waaraan-zijn-moeder-overleed-te-lijf-gaan-met-hitte~ae8664c8/

NU.nl
Halsterse prof wil uitgezaaide kanker te lijf met hitte
https://www.nu.nl/uit-andere-media/6185360/halsterse-prof-wil-uitgezaaide-kanker-te-lijf-met-hitte.html

Papers

Hyperthermia Enhances Efficacy of Chemotherapeutic Agents in Pancreatic Cancer Cell Lines

To further understand the biological effects of hyperthermia (HT) at cellular level, experiments were conducted with pancreatic ductal adenocarcinoma (PDAC) cell lines.

The induction of cell death through apoptosis was seen after 6 h of treatment proving the direct cytotoxic effect of hyperthermia as monotherapy.

Moreover, HT administered in combination with chemotherapy potentiates the cancer cell killing effect without impairing the viability of healthy cells. Indeed, experiments demonstrated an additive or synergistic effect when using the optimal thermal and drug dose. 
Read the full report here

“Systematic review of the registered clinical trials for oncological hyperthermia treatment”, International Journal of Hyperthermia”, Vol. 39, No. 1, 806-812

This article was written to provide a summary of recent research performed on hyperthermia (HT) to treat cancer. In July 2020 ClinicalTrials.gov was used to search all clinical trials about this topic that were conducted between 2000 and 2020 and were investigational studies. Out of 1654 identified studies, 235 were included for further analysis. All of these 235 studies were categorized under hyperthermic intraperitoneal chemotherapy (HIPEC)(52.3%), other regional HT types (18.7%), local HT (19.1%) and whole-body HT (6.4%), respectively. An evolution over all the different HT technologies was observed during the past decades. Research on HT to treat cancer has expanded fast, but more uniform data on efficacy, before moving towards daily clinical application, is required.

Read the complete article here

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