Whole-body thermal treatment (WBTT) increases the temperature of the entire body to a temperature of 41.5°C. A study conducted by ElmediX demonstrated that the application of WBTT in female Aachen minipigs for up to 8 hours was well tolerated.
The key study objectives were:
The animals were evaluated before, during and after WBTT. Minor changes in parameters were observed, but all of these were acceptable. All changes were limited in time and reversible, and the animals remained healthy throughout the entire procedure and during follow-up.
In addition, histopathological analysis of selected key organs showed no thermal treatment-related changes.
In short, these findings contribute and support the application of the ElmediX WBTT device and protocol, enabling it’s translation into human patients suffering from life-threatening diseases.